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Title: Education differentially contributes to cognitive reserve across racial/ethnic groups

Citation Type: Journal Article

Publication Year: 2020

DOI: 10.1002/alz.12176

Abstract: Introduction:We examined whether educational attainment differentially contributes to cognitive reserve (CR) across race/ethnicity. Methods: A total of 1553 non-Hispanic Whites (Whites), non-Hispanic Blacks (Blacks), and Hispanics in the Washington Heights-Inwood Columbia Aging Project (WHICAP) completed structural magnetic resonance imaging. Mixture growth curve modeling was used to examine whether the effect of brain integrity indicators (hippocampal 70 © 2020 the Alzheimer’s Association wileyonlinelibrary.com/journal/alz Alzheimer’s Dement. 2021;17:70–80. AVILA ET AL. 71 volume, cortical thickness, and white matter hyperintensity [WMH] volumes) on memory and language trajectories was modified by education across racial/ethnic groups. Results: Higher educational attainment attenuated the negative impact of WMH burden on memory (β = −0.03; 99% CI: −0.071, −0.002) and language decline (β = −0.024; 99% CI:− 0.044, −0.004), as well as the impact of cortical thinning on level of language performance for Whites, but not for Blacks or Hispanics. Discussion: Educational attainment does not contribute to CR similarly across racial/ethnic groups

Url: https://alz-journals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12176

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Authors: Avila, Justina F; Rentería, Miguel Arce; Jones, Richard N; Vonk, Jet M J; Turney, Indira; Sol, Ketlyne; Seblova, Dominika; Arias, Franchesca; Hill-Jarrett, Tanisha; Levy, Shellie-Anne; Meyer, Oanh; Racine, Annie M; Tom, Sarah E; Melrose, Rebecca J; Deters, Kacie; Medina, Luis D; Carrión, Carmen I; Díaz-Santos, Mirella; Byrd, DeAnnah R; Chesebro, Anthony; Colon, Juliet; Igwe, Kay C; Maas, Benjamin; Brickman, Adam M; Schupf, Nicole; Mayeux, Richard; Manly, Jennifer J

Periodical (Full): Alzheimer's & Dementia

Issue:

Volume: 17

Pages: 70-80

Data Collections: IPUMS USA

Topics: Education, Health, Race and Ethnicity

Countries:

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