Full Citation

Title: Baseline characterization of the ARMADA (Assessing Reliable Measurement in Alzheimer's Disease) study cohorts

Citation Type: Journal Article

Publication Year: 2022

ISBN:

ISSN:

DOI: 10.1002/alz.12816

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Abstract: Introduction: The National Institutes of Health (NIH) Toolbox (NIHTB) provides computerized measures of cognition, emotion, sensation, and motor abilities across the lifespan. The ARMADA (Assessing Reliable Measurement in Alzheimer’s Disease and Cognitive Aging) study validated the NIHTB in individuals across the cognitive aging spectrum. This article reports the characteristics of our sample of participants. Methods: Participants were recruited across nine sites and classified clinically as cognitively normal (NC), with mild cognitive impairment (MCI), or with dementia of the Alzheimer’s type (DAT.) They completed the NIHTB at multiple time points and many had at least one Alzheimer’s biomarker previously obtained. Results: Groups differed with respect to dementia severity levels, as anticipated, but were well-matched across many demographic characteristics. Discussion: The ARMADA study demographics and baseline characteristics provide a suitable sample for validating the NIHTB across the cognitive aging spectrum. Other enriched samples (African American participants, Spanish NIHTB, 85+ years of age) will be reported elsewhere.

Url: https://alz-journals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12816

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Authors: Karpouzian-Rogers, Tatiana; Ho, Emily; Novack, Miriam; Chinkers, Miriam; Bedjeti, Katy; Nowinski, Cindy; Giordani, Bruno; Gershon, Richard; Weintraub, Sandra

Periodical (Full): Alzheimer's & Dementia

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Volume:

Pages: 1-9

Data Collections: IPUMS USA

Topics: Aging and Retirement, Health

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