Full Citation
Title: Factors Influencing Discussion of Cancer Genetic Testing with Health-Care Providers in a Population-Based Survey
Citation Type: Journal Article
Publication Year: 2021
ISBN:
ISSN:
DOI: 10.1159/000515465
NSFID:
PMCID:
PMID:
Abstract: Introduction: Discussion of cancer genetic testing with health-care providers (HCPs) is necessary to undergo testing to inform cancer risk assessment and prevention. Given the rapid evolution in genetic testing practice in oncology, we describe the current landscape of population-level cancer genetic testing behaviors. Methods: A questionnaire including items regarding discussion of cancer genetic testing with HCPs was administered to a nonprobability sample (N = 2,029) of the Texas population. Results: Overall, 11% of respondents discussed cancer genetic testing with HCPs. In multivariable analysis, discussion was significantly related to having a personal history of breast/ovarian/colon cancer (OR = 11.57, 95% CI = 5.34-25.03), personal history of other cancer (OR = 3.18, 95% CI = 1.69-5.97), and health information seeking behaviors (OR = 1.73, 95% CI = 1.12-2.66). Surprisingly , respondents who believed that inherited predispositions in addition to other modifiable risk factors cause cancer were less likely to discuss genetic testing compared to those who did not believe that inherited cancer predispositions cause cancer (OR = 0.54, 95% CI = 0.36-0.79). Discussion: The high discussion rate may be attributed to increased public awareness of genetic testing and adoption of more inclusive clinical genetic testing guidelines. The findings suggest that efforts to increase public awareness of the utility of genetic testing on personalized cancer risk assessment and cancer prevention are needed.
Url: https://doi.org/10.1159/000515465
User Submitted?: No
Authors: Makhnoon, Sukh; Yu, Robert; Cunningham, Sonia A; Peterson, Susan K; Shete, Sanjay
Periodical (Full): Public Health Genomics
Issue:
Volume: 24
Pages: 160-170
Data Collections: IPUMS Health Surveys - NHIS
Topics: Health, Methodology and Data Collection
Countries: