Full Citation
Title: Continued Rapid Increase in Throid Cancer Incidence in California: Trends by Patient, Tumor, and Neighborhood Characteristics
Citation Type: Journal Article
Publication Year: 2014
ISBN:
ISSN:
DOI:
NSFID:
PMCID:
PMID:
Abstract: Background: Thyroid cancer incidence is increasing worldwide. Incorporating 22 years of incidence data through 2009, we extend examination of these trends among a wide array of subgroups defined by patient (age, sex, race/ethnicity, and nativity), tumor (tumor size and stage), and neighborhood (socioeconomic status and residence in ethnic enclaves) characteristics, to identify possible reasons for this increase. Methods: Thyroid cancer incidence data on 10,940 men and 35,147 women were obtained from the California Cancer Registry for 19882009. Population data were obtained from the 1990 and 2000 U.S. Census. Incidence rates and 95% confidence intervals (CI) were calculated and incidence trends were evaluated using Joinpoint regression to evaluate the timing and magnitude of change [annual percentage change (APC) and rate ratios]. Results: The incidence of papillary thyroid cancer continues to increase in both men (APC, 5.4; 95% CI, 4.56.3 for 19982009) and women (APC, 3.8; 95% CI, 3.44.2 for 19982001 and APC, 6.3; 95% CI, 5.76.9 for 20012009). Increasing incidence was observed in all subgroups examined. Conclusions: Although some variation in the magnitude or temporality of the increase in thyroid cancer incidence exists across subgroups, the patterns (i) suggest that changes in diagnostic technology alone do not account for the observed trends and (ii) point to the importance of modifiable behavioral, lifestyle, or environmental factors in understanding this epidemic. Impact: Given the dramatic and continued increase in thyroid cancer incidence rates, studies addressing the causes of these trends are critical
Url: http://cebp.aacrjournals.org/content/23/6/1067
User Submitted?: No
Authors: Horn-Ross, Pamela L.; Lichtensztajn, Daphne Y.; Clarke, Christina A.; Dosiou, Chrysoula
Periodical (Full): Cancer Epidemiology, Biomarkers and Prevention
Issue: 6
Volume: 23
Pages: 1067-1078
Data Collections: IPUMS USA
Topics: Health
Countries: