Full Citation
Title: Joint effects of ethnic enclave residence and ambient volatile organic compounds exposure on risk of gestational diabetes mellitus among Asian/Pacic Islander women in the United States
Citation Type: Journal Article
Publication Year: 2020
ISBN:
ISSN:
DOI: 10.1016/j.annepidem.2020.08.031
NSFID:
PMCID:
PMID:
Abstract: Purpose U.S. Asian/Pacific Islander (API) communities often reside in metropolitan areas with distinct socioenvironmental attributes. Residence in ethnic enclaves, socially distinct areas, is associated with lower gestational diabetes (GDM) risk, yet exposure to air pollution is associated with increased GDM risk. We examined joint effects of ethnic enclaves and air pollution to better understand GDM risk among API women, the group with the highest GDM prevalence. Methods We examined 9,069 API births in the Consortium on Safe Labor (2002-2008). Ethnic enclaves were defined as areas ≥66th percentile for percent API residents, dissimilarity (distribution of API and White residents), and isolation (degree that API individuals interact with API individuals). High levels of 14 volatile organic compounds (VOC) were defined as ≥75th percentile. Four categories were created for each VOC: LowVOC/Enclave (reference), LowVOC/NoEnclave, HighVOC/Enclave, HighVOC/NoEnclave. GDM was reported in medical records. Hierarchical logistic regression estimated odds ratios(OR) and 95% confidence intervals(95%CI) between joint exposures and GDM, adjusted for maternal factors and area-level poverty. Risk was estimated for 3-months preconception and first-trimester exposures. Results Enclave residence was associated with lower GDM risk regardless of VOC exposure. Preconception benzene exposure was associated with increased risk among those outside enclaves [HighVOC/NoEnclave (OR: 3.45, 95% CI: 1.77, 6.72)], and risk was mitigated within enclaves, [HighVOC/Enclave (OR: 2.07, 95%:1.09, 3.94)]. Risks were similar for 12/14 VOCs during preconception and 10/14 during the first trimester. Conclusions API residence in non-enclave areas is associated with higher GDM risk, regardless of VOC level. Enclave residence may mitigate effects of VOC exposure due to lower stress levels.
Url: https://www.sciencedirect.com/science/article/pii/S1047279720303124?via%3Dihub
User Submitted?: No
Authors: Williams, Andrew D; Ha, Sandie; Shenassa, Edmond; Messer, Lynne; Kanner, Jenna; Mendola, Pauline
Periodical (Full): Annals of Epidemiology
Issue:
Volume: 52
Pages: 106
Data Collections: IPUMS NHGIS
Topics: Health, Natural Resource Management, Race and Ethnicity
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